BINDING OF CCCTC-BINDING FACTOR (CTCF) TO THE MINUTE VIRUS OF MICE GENOME IS IMPORTANT FOR PROPER PROCESSING OF VIRAL P4-GENERATED PRE-MRNAS

Binding of CCCTC-Binding Factor (CTCF) to the Minute Virus of Mice Genome Is Important for Proper Processing of Viral P4-Generated Pre-mRNAs

Specific chromatin immunoprecipitation of salt-fractionated infected cell extracts has demonstrated that the CCCTC-binding factor (CTCF), a highly conserved, 11-zinc-finger DNA-binding protein with known roles in cellular and viral genome organization and gene expression, specifically binds the genome of Minute Virus of Mice (MVM).Mutations that di

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Venocentric lesions: an MRI marker of MS?

From the earliest descriptions of MS, the venocentric characteristic VOLUME SHAMPOO AND CONDITIONER of plaques was noted.Recently, numerous MRI studies have proposed this finding as a prospective biomarker for MS, which might aid in differentiating MS from other diseases with similar MRI findings.High field MRI studies have shown that penetrating v

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Research and Application of Regenerative Braking Energy Dispatching System for Heavy Haul Railway Traction Power Supply

The regenerative braking energy of heavy haul railway is abundant but poorly utilized, reflected by low regenerative energy quality and poor economic benefit.In order to reduce cost and save energy, a scheme of regenerative braking energy scheduling system for traction power supply of heavy haul railway is proposed.An energy dispatching device is i

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Environmental enrichment for primates in laboratories

Environmental enrichment is a critical component of Refinement, one of the 3Rs underlying humane experimentation on animals.In this paper I discuss why primates housed in laboratories, which often have constraints of space and study protocols, are a special case for enrichment.I outline a framework for categorising the different types of enrichment

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